Virology & Mycology
Open Access
ISSN: 2161-0517
ISSN: 2161-0517
Department of Infectious Diseases, Fudan University, Shanghai, China
Research Article
Etiology and Prognostic Criteria of Liver Failure in Southeast China: A Multicenter Retrospective Cohort Study between 2018 and 2020
Author(s): Yan Yan*, Chunyan Lyu, Jun Han, Naling Kang, Chantsalmaa Davgadorj, Lina Ge, Meifang Zhou, Dawu Zeng, Richeng Mao and Yuanwang Qiu
The prognosis of patients with Liver Failure (LF) depends significantly on the etiologies and clinical indicators. The retrospective cohort study included 637 LF patients between 2018 and 2020, including the subclasses of Acute Liver Failure (ALF), Subacute Liver Failure (SLF), Acute-on-Chronic Liver Failure (ACLF), Subacute-on-Chronic Liver Failure (SALF), and Chronic Liver Failure (CLF). Multivariate logistic regression analysis was used to screen clinical indicators of death patients. We analyzed the Receiver Operating Characteristic curves (ROCs) and cut-off values to assess prognosis criteria. HBV infection was present in 64.52% of LF patients. SALF (41.36%) is the main subclass of the Hepatitis B Virus-related LF (HBV-LF) group, while chronic liver failure (32.30%) is the main subclass of the non-HBV related LF group in Southeast China. Between 2018 and 2020, the incidence of HB.. View More»
DOI:
10.35248/2161-0517.24.13.281