Cell & Developmental Biology
Open Access

Department of Medicine, Center for Human Reproduction of the Interior, Montevideo, Uruguay

Publications

• Case Report   
  Ovarian Treatment with Autologous Platelet-Rich Plasma Plus Autologous Bone Marrow-Derived Stem Cells: Case Series
  Author(s): Victoria Alzogaray*, Ana Orihuela, Milton Mazza, Rita Vernocchi, Martha Guidobono, Juan Rodriguez Buzzi and Wanda Novick
  
  Introduction: There are limited treatment options for women with severely Diminished Ovarian Reserve (DOR) who experience repeatedly failed In Vitro Fertilization (IVF) cycles. Therefore, most patients resort to using donor oocytes. Ovarian rejuvenation is an innovative procedure intended to reactivate the remaining follicles in the ovary to improve ovarian response in assisted reproduction treatments. Case presentation: Using two treatments at the same time, we enhance the effects of intraovarian Platelet-Rich Plasma (PRP) injection and autologous bone marrow-derived mesenchymal stem cells on ovarian stimulation outcomes in three women referred to a Uruguayan IVF center. Conclusion: Data presented herein suggest that autologous intraovarian PRP infusion plus Stem Cells may restore ovarian function. This may e.. View More»
  

  Abstract PDF