Journal of Proteomics & Bioinformatics
Open Access

Leicester University, UK

Publications

• Review Article   
  Developing High Sensitivity/Specificity Detection Systems for Studying Protein Interactions
  Author(s): Robina Khan*
  
  The study of proteomics succeeds the deciphering of the genetic code; this growing burgeoning area is set to dominate scientific research well into the next decade. Current tools employed in studying protein-protein interactions include antibodies, non-protein scaffolds, fluorescence imaging, split enzymes and the relatively new tool termed Adhirons designed by researchers at Leeds University. Antibodies have been used extensively in protein studies due to the high degree of affinity and specificity however the rise in cost and the length of time required to make antibodies has fuelled efforts to find better alternatives. In this work we report whether Adhirons owing to their small size and high stability can be adapted to assay interactions in cells. It will explore whether current tools widely used in protein studies can debunk the davinchi code for protein-protein interactions. Mos.. View More»
  DOI: 10.35248/0974-276X.19.12.498

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