ISSN: 2329-8901
Microbiology and Systems Biology Group, Netherlands Organization for Applied Scientific Research, Zeist, Netherlands
Roy Montijn Working in Microbiology and Systems Biology Group, Netherlands Organization for Applied Scientific Research,
Zeist, The Netherlands. Sabina Fijan author of peer reviewed journals and area of expertise, as a Researcher credits with many publications in national and international journals
Research
The i-screen: A Versatile Preclinical Platform for Gut Microbiota Studies
Author(s): Frank Schuren*, Valeria Agamennone, Bart Keijser, Edwin Abeln, Jos van der Vossen and Roy Montijn
The gut microbiota is the complex community of microorganisms that inhabit the human intestine. Gut microbes participate in many aspects of human physiology, including health and disease. Food ingredients, drugs and other environmental factors can affect the gut microbiota, with possible consequences on human health.
Progress in microbiome research has significantly stimulated and expanded the interest in technologies to study the potential of different products to modulate the gastro-intestinal ecosystem. In this context we have developed a method, called the i-screen, to evaluate the effects of compounds on the human gut microbiota. The i-screen is an in vitro system that allows the anaerobic cultivation of microorganisms obtained from fecal material, and therefore representative of the highly diverse colonic microbiota. By means of specific analyses, the effects .. View More»
DOI:
10.35248/2329-8901.19.7.212