ISSN: 2329-888X
+44 1300 500008
Department of Food Science, Faculty of Agriculture, Ibb University, Ibb, Yemen
Sadeq Hasan Al-Sheraji, is currently working at Department of Food Science, Faculty of Agriculture, Ibb University, Ibb, Yemen. The number of articles published are 19, the number of times cited by, are 773 and the number of reads include are 12,841. The area of interest in the research was Dairy sciences, Microbiology, Biochemistry, Biosciences, Analytical and Organic Chemistry, Animal and Veterinary Sciences.
Research Article
Nutrigenomic Effects of Fermented Milk Containing Bifidobacterium longum Bb536 on Hepatic Cholesterologenic Genes in Hypercholesterolemic Rats
Author(s): Amin Ismail, Azrina Azlan, Mohd Manap and Sadeq Hasan Al-Sheraji*
The aim of this study was to investigate the effects of fermented milk contains bifidobacteria on plasma lipid levels and selected genes in hypercholesterolemic rats. Effects of Bifidobacterium longum BB536 with prebiotics on body weight of rats, level of bile acids and selected genes were studied. Sprague-Dawley rats were randomly divided into groups. Negative control group received standard diet, positive control group received high-cholesterol diet, and intervention groups received high-cholesterol diet added with fermented milk contains Bifidobacterium longum BB536 in presences of prebiotics. After 8 weeks, body weight, level of bile acids were measured and low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase were investigated in rats’ liver using quantitative real-time polymerase chain reaction. Fermented milk conta.. View More»
DOI:
10.35248/2329-888X.19.7.220