ISSN: 2684-1630
+44 1300 500008
Zoology Department, Cairo University, Cairo, Egypt
Review Article
Malariotherapy: The Old-Renewed Immunotherapeutic Candidate for Systemic Lupus Erythematosus
Author(s): Mostafa A. Abdel-Maksoud* and Saleh Al-Quraishy
Therapeutic options for Autoimmune Diseases (ADS) are very limited with no real curable value. The etiology of this
category of diseases is not clear however; environmental factors are well known to participate in the development of
ADs. Infectious agents like malaria parasites have historically been positively linked with psychiatric and ADs. Jauregg
J Wagner has noticed an obvious amelioration in the neurological abnormalities associated with general paralysis of
the insane (GPI) when some of his patients have encounter malaria infection and subsequently the term
malariotherapy has been introduced. Many years later, Greenwood has noted a lower prevalence of the autoimmune
condition, rheumatoid arthritis (RA) in West Nigerian population and concluded that this low incidence may be a
result of immunological modulation resulting from recurrent exposure to Plasmodiu.. View More»