Advances in Pediatric Research
Open Access
ISSN: 2385-4529
ISSN: 2385-4529
Department of Pediatrics, Pediatric Resident, Ali Asghar Children's Hospital, Iran University of Medical Science, Tehran, India
Research Article
A Cross-Sectional Study to Compare Differences on Clinical and Laboratory Findings in Children with Seropositive and Seronegative Lupus
Author(s): Sharafi Monir*, Salehi Shima, Hossieni Shamsabadi Rozita, Otukesh Hassan and Shairi Reza
Background: Lupus is an inflammatory and autoimmune disease that involves various tissues and organs of the
body. Identification of diagnostic elements to rapid identification of seronegative lupus cases is very important in
order to prevent morbidity and progression of disease. This study aimed to compare clinical and laboratory findings
of seropositive cases with seronegative lupus patients.
Methods: This cross-sectional analytic study was performed on 43 children (17 seronegative and 26 seropositive) with
lupus who were admitted to Ali Asghar Hospital during 2007-2017. Seropositive patients had Anti-Nuclear Antibody
(ANA) titration>1/80, while seronegative patients had ANA titration<1/80 (at the time of disease diagnosis). Clinical
and laboratory findings were compared between two groups.
Results: .. View More»
DOI:
10.35248/2385-4529.23.10.054