Department of Immunology, Laboratory of Medical Immunology, Erasmus University Medical Centre, Rotterdam, The Netherlands
Research Article
Cumulative Incidence and Severity of COVID-19 in Patients with Immune-Mediated Diseases and the Impact of Social Distancing Measures
Author(s): Liesa van der Aa, Marijn van der Sluis, Sandra den Otter, Frank van Boven, MW van der Ent, Paul LA van Daele, Virgil ASH Dalm, Jan AM van Laar, P Martin van Hagen, Saskia Rombach and Maud Hermans*
Background: It is a matter of debate whether patients with Immune-Mediated Diseases (IMD) are at increased risk
infection with SARS-Cov-2 and a severe course of disease. The aim of this study was to evaluate the cumulative
incidence and severity of COVID-19 among patients with immune-mediated diseases and primary immunodeficiency,
taking into account the adherence to social distancing measures.
Methods: A longitudinal cohort study of outpatients of the clinical immunology department of a tertiary medical
Centre was conducted, with their household members as control population. Questionnaires regarding COVID-19,
severity of disease and adherence to social distancing measures were systematically conducted by telephone. The
cumulative incidence was calculated from the beginning of the pandemic until January 29, 2021.
.. View More»
DOI:
10.35248/igoa.21.6.150