Journal of Medical & Surgical Pathology
Open Access

Division of Hematology and Oncology, Department of Internal Medicine, Nashville, Tennessee, USA

Biography

Dr. Das is an Assistant Professor of Medicine in the Department of Medicine Division of Hematology/Oncology at Vanderbilt University Medical Center, at the Vanderbilt-Ingram Cancer Center (VICC). His research interests are in the realm of gastrointestinal (GI) cancer, with a focus on neuroendocrine tumors (NETs), and drug development. They specifically focus upon designing early phase studies to take advantage of salvage DNA repair pathway dependence in DNA damage response (DDR) deficient tumors and to overcome the immunosuppressive tumor microenvironment in refractory tumors through immunotherapy combinations.

Publications

• Research   
  Peritoneal Carcinomatosis in Well-Differentiated Small-Intestinal Neuroendocrine Tumors with Mesenteric Tumor Deposits
  Author(s): Satya Das*, Chanjuan Shi, Tatsuki Koyama, Yi Huang, Raul Gonzalez, Kamran Idrees, Christina Edwards Bailey and Jordan Berlin
  
  Objective: Well-differentiated small-intestinal neuroendocrine tumors (SI-NETs) tend to be biologically indolent.Despite this tendency, they have a predilection for metastasis. Peritoneal involvement is quite common as isunfortunately peritoneal carcinomatosis (PC). PC is a dreaded metastatic complication due to the significant morbidity it creates for patients as well as well as increasing their mortality risk. The risk factors for PC development in SI-NETs remain understudied; however, one such factor may be the presence of mesenteric tumor deposits (MTDs). Methods: We performed a retrospective analysis on 208 well-differentiated SI-NET patient samples, the majority with mesenteric masses, from the pathology archives of Vanderbilt University Medical Center. We sought to explore whether MTD presence was associated with PC, what other patien.. View More»
  

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