ISSN: 2157-7013
+44 1300 500008
Department of Pharmacology, Shandong Medical University, Jinan, Japan
Dr. Sen Zhang is a researcher affiliated with the Department of Pharmacology at Shandong Medical University in Jinan, China. His work focuses on the biology and therapeutic applications of endometrial stem cells (EnSCs). In his 2024 publication, "Endometrial Stem Cells: Biology, Potential, and Therapeutic Applications," Dr. Zhang explores the regenerative capabilities of EnSCs, which are crucial for the cyclical regeneration of the endometrium during the menstrual cycle. He discusses the unique properties of EnSCs, including their self-renewal and multipotency, enabling differentiation into various cell types such as adipocytes, osteocytes, chondrocytes, and myocytes. The paper also highlights the expression of specific surface markers like CD146, PDGFRβ, and SSEA-1, which aid in identifying EnSCs. Additionally, Dr. Zhang examines the influence of ovarian hormones, particularly estrogen and progesterone, on the activity of EnSCs.Dr. Zhang's research delves into the potential therapeutic applications of EnSCs across various medical fields. In regenerative medicine, EnSCs can be utilized to engineer tissue constructs for repairing damaged tissues, including bone, cartilage, and muscle. Their paracrine effects, involving the secretion of growth factors and cytokines, promote wound healing and tissue regeneration.
Opinion Article
Endometrial Stem Cells: Biology, Potential, and Therapeutic Applications
Author(s): Sen Zhang*
DOI:
10.35248/2157-7013.24.15.461