Journal of Clinical Toxicology
Open Access

Department of Genetics, Razi Clinical Research Development Center, Guilan University of Medical Sciences, Rasht, Iran

Publications

• Review   
  The Efficacy of Botulinum Toxin in the Treatment of Herpes Zoster (Shingles) and Trigeminal Neuralgia: A Systematic Review and Meta-Analysis
  Author(s): Mohaya Farzin*, Cyrus Emir Alavi, Sepideh Atef Rad and Habib Eslami Kanarsari
  
  Neuropathic pain, particularly from herpes zoster (shingles) and Trigeminal Neuralgia (TN), can severely impact patients' quality of life. Standard treatments often provide incomplete relief, necessitating alternative therapies. Botulinum Toxin Type A (BTX-A) has been proposed as a potential treatment due to its ability to inhibit pain-mediating neurotransmitters. This study conducted a systematic review and meta-analysis of randomized controlled trials and observational studies on BTX-A for treating herpes zoster and TN. Databases such as PubMed, Cochrane Library, Scopus, and Web of Science were searched for studies published between 2000 and 2023. A total of 12 studies were included, with 6 focusing on TN and 4 on herpes zoster. BTX-A was found to significantly reduce pain intensity in both conditions compared to placebo or standard treatments. For TN, BTX-A showed effectiveness in .. View More»
  

  Abstract PDF