ISSN: 2167-7948
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Department of Pharmacology, International College of Human Nutrition and Functional Medicine, París, 3r 1a Barcelona, Spain
Research Article
Etiopathogenetic Mechanisms in Hashimoto?s Autoimmune Thyroid Disease
Author(s): Isabel García* and Sergio Abanades
Hashimoto’s disease (HD) is an autoimmune thyroid disease often leading to hypothyroidism. The current therapy
for these patients consists in traditional Hormone Replacement Therapy (HRT) to compensate inadequate thyroid
function. However, clinical management of this and other autoimmune disorders usually dismisses the etiologic
component, even when the gold-standard pharmacological treatment is not effective and/or the patient remains
asymptomatic. Here, we propose to dig into the etiopathogenic factors as an attempt to unravel patient’s negative
response to therapy and to improve therapeutic and preventive approaches as standard medical practice as well as to
complement HRT. These factors may include genetic susceptibility, intestinal permeability defects, other pathologies
like celiac disease, gluten intolerance and biopsychosocialstress, gender, se.. View More»