ISSN: 2593-9173
Department of Arts and Science, Hindusthan College of Arts and Science, Coimbatore, Tamil Nadu, India
Research Article
Phytochemical and In vitro Assessment of Synergistic and Biofilm Inhibitory Effects of Parthenium hysterophorus L
Author(s): S.G. Antony Godson*
Objective: Parthenium hysterophorus L. extract was employed to ascertain the antimicrobial attributes in combination with standard antibiotics and its biofilm inhibitory effects against some selected pathogens.
Methods: The ethanolic extract was tested for antibacterial susceptibility against gram positive and gram-negative bacteria by employing agar well diffusion method for Minimum Inhibitory Concentrations (MIC) and Minimum Bactericidal Concentrations (MBC). The synergistic effect of combined plant extract and antibiotics was assessed using time-kill assay and checkerboard methods. Biofilm inhibition assay was also carried out to test inhibitory effect of plant extract.
Results: The plant extract was extracted to have important phytochemicals and it showed antibacterial activity against all the.. View More»
DOI:
10.3389/2593-9173.22.13.502