ISSN: 2165-8048
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Department of Infectious Diseases, Hull University Teaching Hospitals, Hull, United Kingdom
Dr. Shah Rukh Malik works in the Department of Infectious Diseases, Hull University Teaching Hospitals, Hull, United Kingdom, is a well known researher and one of his famous works are Langerhans Cell Histiocytosis Presenting with Central Diabetes Insipidus in an Adult: A Case Report with a Discussion on Differential Diagnosis, Diagnostic Workup and Treatment
Case Report
Langerhans Cell Histiocytosis Presenting with Central Diabetes Insipidus in an Adult: A Case Report with a Discussion on Differential Diagnosis, Diagnostic Work up and Treatment
Author(s): Najeeb Shah*, Harshal Deshmukh, Shiva Mongolu, Muhammad Jawaid Akbar, Shah Rukh Malik, Shahbaz Nazir and Somil Rastogi
Langerhans Cell Histiocytosis (LCH) is rare in adults; the condition affects 1-2 patients per million annually in the
general population. Diabetes Insipidus (DI) is a common manifestation of Langerhans Cell Histiocytosis (LCH)
although its reported frequency varies in different series. The pathogenesis of the condition is not precisely
understood. Infiltration of the hypothalamic-pituitary axis by Langerhans-like cells has been reported in 50% of
autopsied patients. Central Diabetes Insipidus (CDI) can be familial, idiopathic or secondary and is a disorder
characterised by polyuria, polydipsia and formation of hypotonic urine... View More»
DOI:
10.35248/2165-8048.21.11.333