Journal of Depression and Anxiety
Open Access

Department of Psychiatry, University of North Carolina, North Carolina, USA

Publications

• Research Article   
  A Newly Observed Negative Association between Cell Membrane Capacitance and Depression Using Data Measured by a HYDRA ECF/ICF Bio-Impedance Spectrum Analyzer and Cole Model
  Author(s): Xinrui Liu* and Shaoyi Zhang
  
  Cell’s bilayer phospholipid membranes work as insulators that separate the extracellular matrix and cytoplasm, creating a charge gradient across the cell membrane. Cell membrane capacitance, together with membrane resistance, impacts how fast the cell responds to the flow of ions currents. And for neurons, it affects how the neurons integrate electric signals and their synaptic efficacy. In this study, we performed logistic regression and used statistical analysis, and found a significant correlation with a relatively large R-squared value between depression and cell membrane capacitance. Objective: This study aims to study if the lower cell membrane capacitance correlates with an increased rate of depression in participants aged 8-49 years old. Data collection: Data used in this study were collected in the 1999-2000 and 2001.. View More»
  DOI: 10.35248/2167-1044.24.13.531

  Abstract HTML PDF