ISSN: 2684-1266
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Department of Biotechnology, Assam University, India
Shouharth choudhury's background is from bioinformatics . His department is from school of life science, silchar.Department of Biotechnology, Assam University, Silchar, Assam, India;3 Department of Life Science and Bioinformatics, , Silchar, Assam, IndiaIndia, Assam University, Silchar, Assam, India Department of Life Science and Bioinformatics
Research Article
In Silico Analysis of the FOXP3 Transcription Factor Associated with T-Cell Oncogenesis
Author(s): Shouhartha Choudhury*
Background: The X chromosome encoded FOXP3 gene is a unique regulator of the T-cell differentiation and
immunosuppressive function. The nuclear transcription factor FOXP3 gene regulates lineage-specific differentiation
in the Treg crucially maintenance of the immune homeostasis. The regulatory T-cell (Treg or CD4+ cells) play a role
in the immune response for self-antigens, allergens, and tumours. However, FOXP3 gene function is inconsistent in
tumorigenesis such as tumour-suppressive and tumour-promoting. A recent report suggested the FOXP3 gene repress
tumorigenesis per effects on proliferation and apoptosis.
Objective: My objective was to investigate the FOXP3 gene from the FOX family in between Homo sapiens and Musmusculus. The study of the FOXP3 gene is currently mandatory to explore the molecular mech.. View More»
DOI:
10.35248/2684-1266.20.6.120