ISSN: 2155-9554
+44 1478 350008
Department of Dermatology, Out-patient Service, Udine, Italy
Research Article
Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil without Propylene glycol: A 6-month,
Multicentre, Real-life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The &ldq
Author(s): Paola Nappa, Massimo Milani*, Klause Eisendle, Mario Puviani, Giovanni Zanframundo, Fabrizio Vaira, Sonia Torti, Marco Tomassini, Elena Saccani, Nicolò Rivetti, Fabrizio Presta, Luigi Pisano, Laura Alessi, Stefania Farina, DonatoDi Nunno, Arianna Corsini, Silvia Bondino, Annunziata Bartolotta, Stefania Barruscotti, Stefania Bano, Ylenia Balice, Alex Arena, Valentina Amadu and Maria Catena Aloisi
Background and trial objectives: A new propylene glycol (PG)-free 5% minoxidil (PG-Free-Mnx) lotion has been recently commercialized. Clinical efficacy and local tolerability have been, so far, documented in a limited number of patients. The aim of this study was to evaluate the clinical efficacy, cosmetic acceptability, and local tolerability of 6-month application of this new PG-Free Mnx lotion in a real-life situation.
Materials and methods: The NOMINAL (NO-PG MINoxidil reAL life study) trial was performed in 22 out-patients Italian dermatology clinics. A total of 196 subjects of both sexes with a diagnosis of AGA/FAGA were enrolled in the trial, after their written informed consent. PG-Free-Mnx lotion was applied 1 ml twice daily for 6 months. Clinical efficacy was evaluated in an open fashion in all the enrolled subjects with a 5-grade .. View More»
DOI:
10.35248/2155-9554.21.12.566