Journal of Leukemia
Open Access

Department of Medicine, Kahn Sagol Maccabi Research & Innovation Center, Tel-Aviv, Israel

Publications

• Research Article   
  Beta-Blockers Therapy is Associated with Shorter Time to First Treatments in Early-Stage Chronic Lymphocytic Leukemia
  Author(s): Tamar Tadmor*, Guy Melamed, Hilel Alapi, Sivan Gazit, Tal Patalon and Lior Rokach
  
  Introduction: Beta blockers are among the most used class of drugs for the treatment of hypertension, arrythmias and congestive heart failure. Chronic Lymphocytic Leukemia (CLL) is the most frequent leukemia in western countries, and it involves elderly patients, who presents with past medical history including hypertension, arrythmias and heart disease. Methods: In the current study, we aimed to retrospectively explore the effect of the use of beta-blocker, on Time To First Treatment (TTFT) in a large cohort of 3,474 patients with asymptomatic CLL who were under watch and wait approach. Data obtained from electronic medical records of Maccabi Healthcare Services (MHS) members, after receiving approval from the institution's ethical committee. Results: Median follow-up of the entire cohort was 1745 days (57 mon.. View More»
  DOI: 10.35248/2165-7556-24.12.387

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