Fungal Genomics & Biology
Open Access
ISSN: 2165-8056
ISSN: 2165-8056
Department of Chemistry of Natural Products, Medicinal Chemistry and Organic Synthesis, Mumbai University, Mithagar Road, Mulund (E), Mumbai 400081, India
Research Article
Biotechnological Transformation of Citronellene and Citronellol: By Fungus Rhizopus oryzae (ATCC 9363) Leading to Interesting Conversions through Oxidations and Rearrangements
Author(s): Sujata V. Bhat*, Sayali J. Mestry and Manisha O. Gupta
In this study, microbial transformation of monoterpenes (-)-citronellol, (±) citronellene (dihydromyrcene) using Rhizopus oryzae in a Potato Dextrose Broth (PDB) medium was investigated. The major bioconversion product of citronellene was found to be dihydroxycitronellene, which is formed by dihydroxylation of the terminal 6, 7-double bond. On the contrary, (3S)-citronellol yielded 7-hydroxy citronellol as a major product. Several minor products including rose oxide, rose glycol, isopulegol, artemisia-triene, 1, 8-nonan-diol-8-methyl, citronellyl phenyl acetate were obtained from (-)-citronellol. Whereas camphene, camphor, α -pinene, Isopulegone, terpinene-4-ol, and 1, 8-nonan-diol-8-methyl are the minor products obtained from (±) -citronellene. Hence, dihydroxylations and hydroxylation at the selective position of a diene with the help of microbe.. View More»
DOI:
10.35248/2165-8056.23.13.207