Journal of Infectious Diseases & Preventive Medicine
Open Access

Department of Vaccine and Drugs Development, The National Research and Innovation Agency, Jakarta, Indonesia, Republic of Korea

Publications

• Research Article   
  A Novel Limosilactobacillus reuteri Strain Byun-re-01 Exhibits Promising Probiotic Properties for Further Use as Preservatives: An In Vivo and In Silico Study
  Author(s): Seungchan Cho, Sung June Byun and Sukchan Lee*
  
  Antibiotics had been a pivotal substance to be supplemented in the food for poultry flock with a main purpose to improve their yields in order to gain profits. However, its long-term use costs some adverse effects such as resistance and tolerance. Hence, a new platform is of urgency to figure out. We discovered that our probiotic bacteria, which through the whole-genome sequencing was identified as Limosilactobacillus reuteri strain Byun-re-01 (L. reuteri Byun- re-01), exhibited promising biological properties to substitute the existing use of antibiotics. Oral administration of L. reuteri Byun-re-01 was shown to provide local protection by producing anti-inflammatory cytokines mainly IFN-β and IFN-γ in mRNA levels. In addition, they suppressed the expression of viral capsid mRNA of MNV indicating their antiviral activity. They w.. View More»
  DOI: 10.35841/2329-8731.22.10.271

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