Journal of Antivirals & Antiretrovirals
Open Access
ISSN: 1948-5964
+44 1300 500008
ISSN: 1948-5964
+44 1300 500008
Department of Microbiology, Chittagong Medical College, Chattogram, Bangladesh
Research Article
Comorbidities of COVID-19 Patients with Low Cycle Threshold (Ct) Value of Nucleocapsid (N) Gene: An Application to Cluster-Based Logistic Model
Author(s): Sujan Rudra, Shuva Das*, Md Ehsanul Hoque, Abul Kalam, Mohammad Arifur Rahman, Swagata Nandy Shizuka and Tazrina Rahman
Background: Coronavirus Disease 2019 (COVID-19) is a health crisis throughout the world. The widely used
Real-time Reverse Transcriptase Polymerase Chain Reaction (rRT-PCR) method is most capable of describing the
patient’s condition. Comorbidities can make patients more critical.
Methods: In this study, we shed light on the low Cycle Threshold (Ct) value of the N gene in the rRT-PCR test
of the COVID-19 patients who had comorbidities, cure rate, and the needfulness of ICU (Intensive Care Unit)
management. We had conducted the research in the Molecular Biology Laboratory of Chittagong Medical College
between May and August 2020, then took the telephone interview with 300 positive patients who fulfilled the study
criteria. We applied cluster-based logistic regression to analyze the data.
Results:.. View More»
DOI:
10.35248/1948-5964.21.13.214