Journal of Clinical & Experimental Dermatology Research
Open Access

Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Kurume, Japan

Publications

• Research Article   
  Laser Scanning Confocal Microscopy for Diagnostics of Brunsting-Perry Type Cicatrical Pemphigoid Cases, along with Review of Literature
  Author(s): K Osipowicz*, B Jakubowska, C Kowalewski, T Hashimoto and K Wozniak
  
  Background: In the literature there are a few reported cases of cicatrical pemphigoid Brunsting-Perry type (CPBP). CPBP is well clinically characterized by clinical research, however is heterogeneous in a term of immunological findings. Laser scanning confocal microscopy (LSCM) is a helpful tool for diagnostics of cicatricial pemphigoid in general, especially when circulating antibodies are not detectable. Objectives: Application of LSCM for the first time in a case with clinical features of CPBP and review the literature. Methods: Skin biopsy was taken for LSCM studies. LSCM technique relies on comparison between the location of IgG/IgA deposits and basement membrane zone (BMZ) markers: antibodies directed to laminin 332 served as a marker of lower part of lamina lucida, whereas antibodies to type IV collagen served as .. View More»
  

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