ISSN: 2161-1149 (Printed)
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Department of Pediatrics, Cairo University, Cairo, Egypt
Dr. Talaat HS, a distinguished expert and author has published several articles on Pediatrics, works in the Department of Pediatrics, Cairo University, Cairo, Egypt.
Research Article
Markers for Subclinical Inflammation in Egyptian Children with Familial Mediterranean Fever: Splenomegaly and Mean Platelet Volume
Author(s): Talaat HS, Sheba MF, Mohammed RH and Ibrahim MFM*
Background: Familial Mediterranean fever (FMF) is an auto-inflammatory systemic disease, of an autosomal recessive
inheritance, that is characterized by recurrent episodes of fever, peritonitis, pleuritis, pericarditis, and/or arthritis;
MEFV is the responsible gene.
Aim: To detect the correlation of Mean Platelet Volume (MPV) and splenomegaly as subclinical inflammatory
markers in children with FMF at the attack-free periods.
Methods: This cross-sectional study included 40 pediatric patients diagnosed clinically and according to gene
mutations already with FMF and were following-up at the Rheumatology Outpatient Clinic, Children's Hospital,
Cairo University. Abdominal ultrasonography was done all patients to detect splenomegaly; MPV was measured as
well.
Results: Patients was.. View More»
DOI:
10.35248/2161-1149.20.10.258