Journal of Clinical Trials
Open Access

Department of Internal Medicine, Kafrelsheikh University, Kafr Elsheikh, Egypt

Publications

• Research Article   
  Management of A COVID-19 Spike Protein based Vaccine which Inducing Blood Clots and Damage to ACE2 Expressing Cells-A Double-Edged Sword
  Author(s): Mahmoud Elkazzaz*, Yousry Abo-amer and Tamer Haydara
  
  The interaction between various COVID-19 vaccines and our immune system's response to mediate protection or susceptibility to SARS-CoV-2 is in the very initial stages of understanding. Hundreds of 2019 Corona virus disease targeting vaccines are currently in progress, but success is unknown. Most of the vaccine candidates use a protein- based subunit (spike protein-based vaccine)-so, instead of using a complete pathogenic virus, they are built on a small component of it, such as a protein found in its outer shell. That protein is administered to patients in a high dose, with the aim of inducing a fast and strong reaction by the human immune system. Spike protein-based vaccines were granted emergency approval within a limited period of time and are now being rolled out. This type of vaccine provides our cells with signals to express a component of what is called th.. View More»
  

  Abstract PDF