Cell & Developmental Biology
Open Access

Department of Anatomy, University of Medical Sciences, Ondo City, Nigeria

Publications

• Research Article   
  Immunotoxicological Investigation of The Intracranial Auditory Centers In Pyrethroids Formulation Treated Wistar Rat
  Author(s): Kingsley A Iteire*, Adejumo A Adenike, Tebamifor T Witness and Onoriode Oyiborhoro
  
  Purpose: The use of pesticides and their potential impact on public health are of great concern. Recent studies on the pathophysiology of neurodegenerative diseases have suggested that chronic exposure to pyrethroids could be associated with alterations in the central auditory pathways. This study was therefore aimed at evaluating the neurotoxicity of pyrethroids on the intracranial auditory relay-centers in adult wistar rats. Methods: Forty adult wistar rats of both sexes with average weight of 180g were assigned into five groups (n=8). Groups A, B, and C were treated with known pyrethroids formulation containing Cyfluthrin, Imiprothrin, and Prallethrin, diluted with olive oil to form 25%, 50% and 75% concentrations. Groups D and E were administered distilled water and olive oil once treatment negative and positive controls, respectively. The treatment lasted for duration of forty da.. View More»
  DOI: 10.35248/2168-9296.20.9.202

  Abstract HTML PDF