ISSN: 2471-9315
+44 1300 500008
Department of Biotechnology, College of Natural and Computational Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Review Article
Genetic Diversity in Escherichia coli
Author(s): Benyam Zenebe*, Tesfaye Sisay and Gurja Belay
E. coli are genetically diverse bacteria which can live in different habitats. The E. coli genome has two components:
The core genome which contains essential genes and is shared among all strains of the species; and the accessory
genome which is highly variable among strains encompassing many mobile genetic elements. Despite the extensive
dynamics in the genomic content over evolutionary period, the genome size of E. coli seems to have been conserved
due to processes of continuous gene gain and gene loss. Mobile genetic elements give strains of E. coli better
adaptability to different environments such as the ability to resist antibiotics and to escape immune responses and
establish infection in various hosts. Mobile genetic elements have been detected in both commensal and pathogenic
strains. Horizontal gene transfer in the fo.. View More»
DOI:
10.35248/2471-9315.24.10.311