Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Tokai University Hospital, Isehara-shi, Kanagawa, Japan
Dr. Tetsu Akiyama is currently working in Tokai University Hospital, Isehara-shi, Kanagawa, Japan. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended his valuable service towards the scientific community with his extensive research work.
Mini Review
Intestinal Dysbiosis and Probiotics in COVID-19
Author(s): Yasunari Kageyama, Tetsu Akiyama and Tsutomu Nakamura*
The COVID-19 pandemic has been an emerging threat to global public health. Several lines of evidence suggest that the causative virus SARS-CoV-2 infects the human intestinal epithelial cells as well as airway epithelial cells, suggesting that the enteric infection of SARS-CoV-2 has destructive effects on the intestinal microbiota and subsequently airway physiology and immunity through the gut-lung axis. Despite the important roles of the gut-lung axis in the antiviral immunity, only limited information is currently available concerning COVID-19-specific changes in the gut microbiome. This review summarizes recent knowledge of intestinal dysbiosis associated with COVID-19 patients and its potential contribution to the respiratory symptoms through the gut-lung axis. We also discuss the possibility of prophylactic and therapeutic use of probiotics in COVID-19, including our ongoing trial.. View More»
DOI:
10.35248/2167-0870.20.10.421