Poultry, Fisheries & Wildlife Sciences
Open Access

Department of Veterinary Pathobiology, College Station, Texas A&M University, TX, 77843, USA

Biography

Dr. Ficht’ research areas include studies of the molecular pathogenesis of intracellular bacterial pathogens, and the development of vaccines and diagnostic tests against zoonotic diseases. He has authored more than 70 scientific publications in refereed journals, 150 abstracts, six book chapters, and made several hundred scientific presentations. Dr. Ficht has been the research training mentor for and chaired or co-chaired 21 graduate students and 27 undergraduate students and trained 10 post-doctoral fellows in his own laboratory while serving on the graduate committees of 50 PhD graduate student advisory committees. 

Publications

• Research Article   
  Bacillus anthracis Sterne Strain 34f2 Vaccine Antibody Dose Response by Subcutaneous and Oral Administration
  Author(s): Jamie Benn Felix*, Sankar P Chaki, Thomas A Ficht, Allison C Rice-Ficht and Walt Cook
  
  Anthrax (Bacillus anthracis) is a zoonotic disease endemic to environments worldwide. Spores, the dormant form of the bacteria, can survive for decades in nature’s harshest environments and maintain their viability to cause disease. Outbreaks are common in free-ranging livestock and wildlife, thus making anthrax an economically and ecologically important disease. The currently available vaccine to protect livestock is a suspension of B. anthracis Sterne Strain 34F2 spores in saponin (Sterne vaccine). However, it is only available as a subcutaneous injection which is an impractical method of prevention for wildlife. Oral vaccination is the ideal method for free-ranging wildlife, but the Sterne vaccine has never been thoroughly evaluated for oral administration. The current study evaluated the antibody titers induced in mice by subcutaneous or oral vaccination with three different.. View More»
  DOI: 10.35248/2375-446X.19.7.206

  Abstract HTML PDF