Journal of Probiotics & Health
Open Access

Department of Pediatrics, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas 77030, United States

Biography

Thomas K Hoang in Department of Pediatrics, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas 77030, United States.. Sabina Fijan author of peer reviewed journals and area of expertise, as a Researcher credits with many publications in national and international journals

Publications

• Research   
  Human Breast Milk Promotes the Immunomodulatory Function of Probiotic Lactobacillus reuteri DSM 17938 in the Neonatal Rat Intestine
  Author(s): Thomas K Hoang, Jasmin Freeborn, Ting Wang, Tu Mai, Baokun He, Sinyoung Park, Dat Q Tran, Stefan Roos, J Marc Rhoads and Yuying Liu*
  
  Background and objective: Breast milk has many growth-promoting and immune-active components, including transforming growth factor-β, lactoferrin, lysozyme, immunoglobulin A, and prebiotics such as the human milk oligosaccharides. Treatment with Lactobacillus reuteri DSM 17938 (LR), a probiotic with immunomodulatory functions, significantly increases regulatory T cells (Tregs) in the intestinal mucosa of newborn suckling rats. In humans, treatment with LR of infants with colic reduces crying optimally if the infants are breast-fed. Therefore, we examined the effects of human breast milk (HBM) on LR-associated immune modulation. Methods: Newborn rats were divided into 8 feeding groups, including dam-fed ± LR (106 CFU/kg bw/day, daily), formula-fed ± LR, formula with 20% (v/v) HBM-fed ± LR, and HBM.. View More»
  DOI: 10.35248/2329-8901.19.7.210

  Abstract HTML PDF