Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Clinical Infectious Diseases, Kawasaki Medical School, Matsushima, Kurashiki, Okayama 701-0192, Japan
Research Article
Evaluation of Virus Detection in Pediatric Patients Hospitalized with Respiratory Tract Infections Using Quantitative Multiplex PCR
Author(s): Yuto Yasui, Tomohiro Oishi*, Atsushi Kato, Satoko Ogita, Takahiro Eitoku, Hideo Enoki and Takashi Nakano
Respiratory Tract Infections (RTIs) are common in children. Viruses are known to be related to most pediatric infections. However, some pediatric cases of RTI have been found to be associated with multiple viruses. In this study, we collected samples from the nasopharynx of all pediatric patients admitted to our hospital with RTI between April, 2022 and March, 2023 and performed multiple quantitative real-time Polymerase Chain Reactions (PCRs). Out of 77 patients involved, 67 (87.0%) tested positive for some or the other virus. Rhinovirus was the most detected, followed by the Respiratory Syncytial (RS) virus and parainfluenza virus type 3. Among the patients, 18 (26.9%) had multiple viral infections and 14 had complications associated with obstructive respiratory diseases, including bronchial asthma, acute bronchiolitis and asthmatic bronchitis. Furthermore, some cases were found to .. View More»
DOI:
10.35248/2167-0870.25.15.579