ISSN: 2167-7948
+44 1300 500008
Department of Clinical Laboratory, Hyogo Medical University Hospital, Nishinomiya, Japan
Dr. Toru Watanabe is a distinguished researcher affiliated with the Department of Clinical Laboratory at Hyogo Medical University Hospital in Nishinomiya, Japan. His research primarily focuses on immunology, endocrinology, and the development of novel diagnostic and therapeutic strategies for thyroid diseases. Academic Background and Affiliation: Hyogo Medical University Hospital, Nishinomiya, Japan: Dr. Watanabe serves in the Department of Clinical Laboratory, engaging in research related to clinical diagnostics and laboratory medicine. Research Contributions: Dr. Watanabe has made significant contributions to the understanding of thyroid diseases and autoimmune disorders. Notable publications include: "Autoantibodies as Biomarkers in Thyroid Diseases" Journal: Journal of Thyroid Disorders & Therapy Summary: This review explores the potential of autoantibodies as diagnostic and prognostic biomarkers in various thyroid diseases. "Thyroid-Stimulating Antibody/Thyroid-Stimulating Hormone Receptor Antibody in Graves' Disease" Journal: Endocrine Practice Summary: This study investigates the role of thyroid-stimulating antibodies in Graves' disease, providing insights into autoimmune thyroid disorders. "Adenosine Inhibits TNFα-Induced MMP-3 Production in MH7A Rheumatoid Arthritis Synoviocytes via A2A Receptor Signaling" Journal: Scientific Reports Summary: This research examines the anti-inflammatory effects of adenosine in rheumatoid arthritis, highlighting its potential therapeutic applications.
Review
Autoantibodies as Biomarkers in Thyroid Diseases
Author(s): Masayoshi Nakano*, Ayako Miyazaki, Hiroe Konishi, Rika Yukimatsu, Toru Watanabe and Masahiro Koshiba
Thyroid diseases are common pathologies in primary care settings, and many patients with such diseases are treated by physicians who are not specialized in thyroid conditions. To diagnose such diseases earlier, some biological biomarkers have been identified. Anti-TSH receptor antibodies, which are considered the cause of Graves’ disease, are autoantibodies that bind to TSH receptors and activate the thyroid gland. The measurement of anti-TSH receptor antibodies is crucial for diagnosing, managing, and monitoring the treatment of Graves’ disease. This test has high sensitivity and specificity as a diagnostic tool. Conversely, antibodies against the TSH receptor do not have just one property; thus, the anti-TSH receptor antibody assay system could be improved to distinguish the different functions of antibodies. Patients diagnosed with thyroid disorders can generate TSH rec.. View More»
DOI:
10.35248/2167-7948.23.12.295