Journal of Cancer Science and Research
Open Access
ISSN: 2576-1447
+44 1478 350008
ISSN: 2576-1447
+44 1478 350008
Department of oral and maxillofacial surgery, Oxford Dental College, Banglore, Karnataka, India
Review Article
Targeted Magnetic Nanoparticle Hyperthermia for the Treatment of Oral Cancer
Author(s): Santosh BS, Harish Kumar A, Tulima Begum*, Supriya Bhandage and Jerin Jose
Oral squamous cell carcinoma is a common cancer worldwide. Apart from surgery, chemotherapy and radiotherapy
have been tried in the treatment of oral cancers. However these treatment modalities have their own side effects in
the course of treatment. Recently, several methods such as targeted therapy alone or in combination with
chemotherapy have been employed for the treatment of oral cancer. Hyperthermia in the recent times with the use of
mangnetic nanoparticles (MNP) have been shown as a promising therapy in reducing the disease. This article applies
a review of literature to understand the basic features of hyperthermic cell death, the mechanism of action of
magnetic nanoparticles hyperthermia, application of MNPs in the diagnosis and treatment of oral cancer, the
potential hazards, and the future prospectives... View More»
DOI:
10.35248/2576-1447.22.7.519