ISSN: 2161-0940
+44 1300 500008
Department of Human Physiology, University of Uyo Akwa, Ibom State, Nigeria
Department of Human Anatomy, University of Uyo Akwa, Ibom State, Nigeria Department of Human Anatomy, University of Uyo Akwa, Ibom State, Nigeria Department of Human Anatomy, University of Uyo Akwa, Ibom State, Nigeria
Research Article
Aloe Vera Heals Gastric Ulcer in 7 Days than Omeprazole and Cimetidine : Prostaglandin?
Author(s): Jimmy EO*, Umoh IU and Usun VJ
Peptic ulcer disease is becoming a very common disease as it is associated with lifestyle e.g eating habits more than infection, by bacteria, H. pylori [1]. There are many treatments for the disease which are not very potent for the eradication of the disease.
A comparative study was therefore carried out with Aloe Vera, cimetidine and omeprazole to arrive at the most potent treatment drug. A total of thirty (30) male and female rats were used for the study. The Aloe Vera extract with LD50 of 1870.83 mg/kg was administered in three dosages; low, medial and high, 187.08 mg/kg, 374.42 mg/kg and 561.25 mg/kg respectively in groups (3-4) while cimetidine and omeprazole in groups V and VI respectively for 28 days. Gastric HCl increased significantly p<0.1 in group 3 as compared to the control but was not signif.. View More»