Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Department of Medical Laboratory Sciences, Universitatsklinikum Regensburg, Regensburg, Germany

Biography

Dr. Ute Hubauer is currently working in University Hospital Regensburg, Germany. Publications include N-acetyl-ß-D-glucosaminidase is predictive of mortality in chronic heart failure: a 10-year follow-up, Urinary N?terminal pro?brain natriuretic peptide: prognostic value in patients with acute chest pain, N-acetyl-b-D-glucosaminidase: A potential cardiorenal biomarker with a relevant impact on ICD shock therapies and mortality etc

Publications

• Research Article   
  Evaluation of a Multimarker Panel in Chronic Heart Failure: A 10 Years Follow-Up
  Author(s): Susanne Bauer*, Christina Strack, Ute Hubauer, Ekrem Ücer, Stefan Wallner, Andreas Luchner, Lars Maier and Carsten Jungbauer
  
  Background: Chronic heart failure is a complex disease associated with various pathophysiological and biochemical disorders. We assessed the 10 years prognostic role of a multimarker panel of markers for myocyte stress (GDF-15), extra-cellular matrix remodeling (Galectin-3, mimecan, TIMP-1), inflammation (Galectin-3), myocyte injury (hs-TnT) and angiogenesis (endostatin, IBP-4, IGF-BP-7, sFlt-1 and PLGF) head-to-head with the biochemical gold-standard NT-proBNP. Methods: Blood samplesfrom 149 patients with heart failure were analysed. After 10 years of follow-up (median follow-up 104 months, IQR 43-117), data regarding rehospitalisation for chronic heart failure and all-cause-mortality were acquired. Results: Regarding Kaplan Meier analysis, all markers, dichotomized according to you denindex,.. View More»
  

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