ISSN: 2329-8901
Microbiology and Systems Biology Group, Netherlands Organization for Applied Scientific Research, Zeist, Netherlands
I am a biologist with a background in environmental science and nature conservation. During my PhD in Amsterdam I studied the bacterial communities in the intestinal tract of springtails, tiny soil animals. Afterwards I shifted my attention to the human microbiome: I now organize and execute studies aimed at uncovering the role of the microbiota in modulating health and preventing disease.
Research
The i-screen: A Versatile Preclinical Platform for Gut Microbiota Studies
Author(s): Frank Schuren*, Valeria Agamennone, Bart Keijser, Edwin Abeln, Jos van der Vossen and Roy Montijn
The gut microbiota is the complex community of microorganisms that inhabit the human intestine. Gut microbes participate in many aspects of human physiology, including health and disease. Food ingredients, drugs and other environmental factors can affect the gut microbiota, with possible consequences on human health.
Progress in microbiome research has significantly stimulated and expanded the interest in technologies to study the potential of different products to modulate the gastro-intestinal ecosystem. In this context we have developed a method, called the i-screen, to evaluate the effects of compounds on the human gut microbiota. The i-screen is an in vitro system that allows the anaerobic cultivation of microorganisms obtained from fecal material, and therefore representative of the highly diverse colonic microbiota. By means of specific analyses, the effects .. View More»
DOI:
10.35248/2329-8901.19.7.212