ISSN: 2329-8731
+44 1300 500008
Department of Biomedical Engineering, Texas A&M University, College Station, USA
Vanderlei Salvador Bagnato simultaneously completed a Bachelor's Degree in Physics - USP, and Materials Engineering - UFSCar in 1981 and a Ph.D. in Physics - Massachusetts Institute of Technology - MIT in 1987. He is currently a full professor at the University of São Paulo and director of the Institute of Physics of São Carlos. Published about 700 articles in specialized journals. It has 29 book chapters and 7 published books. He has supervised more than 100 theses between master's and doctoral degrees, in the areas of Physics, Dentistry, and Medicine. Received several awards and honors.
Mini Review
Antimicrobial Photodynamic Action in Medical Materials: A Novel Thriving
Area for Hospital Pneumonia Prevention
Author(s): Kate C. Blanco*, Lucas D. Dias, Amanda C. Zangirolami and Vanderlei S. Bagnato
Background: Endotracheal tubes, used for mechanical ventilation assistance for bedridden patients, are conducive to
developing microbial biofilms due to the accumulation of body fluids. These systems are closely linked to hospital
pneumonia by dispersing these cells from microbial biofilm from endotracheal tube to the lung.
Objective: Describe endotracheal tubes' functionalization with photosensitizers such as curcumin, the progress, and
perspectives of this research.
Methods: An antimicrobial endotracheal tube was developed through the functionalization of its surface with a
photosensitizer activated by light for the generation of reactive oxygen species, which inactivate microorganisms.
Therefore, the prevention of pneumonia associated with mechanical ventilation was the object of a study to reach a
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DOI:
10.35248/2329-8731.21.9.211