Journal of Proteomics & Bioinformatics
Open Access

Department of Centre for Integrative Medicine and Research, University of All India Institute of Medical Sciences (AIIMS), New Delhi, India

Publications

• Research   
  Computational Profiling of Inflammatory and Coagulation Responses in COVID-19 via Ribonucleic Acid Sequencing (RNA-Seq)
  Author(s): Varun Chhabra*
  
  The COVID-19 pandemic, driven by the SARS-CoV-2 virus, has emerged as an unparalleled global public health crisis. Despite extensive research efforts, the precise etiology of this disease remains enigmatic. In this study, we employ in-silico methods to analyze publicly available gene expression datasets from the Gene Expression Omnibus (GEO), aiming to uncover the underlying molecular mechanisms. Gene expression datasets were retrieved from GEO and differential gene expression patterns were identified using the GEO 2R pipeline. Subsequent analyses included the generation of heatmaps, Principal Component Analysis (PCA), construction of Protein-Protein Interaction (PPIs) networks and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway predictions through network analyst and Database for Annotation, Visualization and Integrated Discovery (DAVID). We also exa.. View More»
  DOI: 10.35248/0974-276X.24.17.662

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