ISSN: 2155-9600
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Sanzyme Biologics Pvt Ltd, India
Research Article
Co-supplementation of Probiotic - Bacillus coagulans SNZ 1969® and Whey Protein Improves Amino Acid Absorption and Reduces the Incidence of Acne in Healthy Adults: A Randomized, Double-Blind, Crossover Study
Author(s): Raunak J. Soman, Dhruv Soman and Venkata Kishan Pokuri*
Background: Probiotics enhance absorption of amino acids from protein supplements. This study evaluated the effect of Bacillus coagulans SNZ 1969® (probiotic) on amino acid absorption rates and incidence of acneiform lesions after whey protein supplementation.
Methods: Healthy adults aged 18 years-30 years were randomized to receive either whey protein (25 g) and probiotic or whey protein (25 g) alone once daily for 14 days with a 21-day washout period. The primary endpoint was area under the plasma concentration vs time curve (AUC0-4h) for amino acids. The secondary endpoints included: Cmax, Tmax, incidence of acneiform lesions, and safety.
Results: Of 30 participants, 26 were treated in the first period, of whom, 22 completed the study. The mean (SD) age was 26.0 (3.4) .. View More»
DOI:
10.35248/2155-9600.24.14.51