Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Research and Development, Lonza Consumer Health Inc, 412 Mt. Kemble Ave. Suite 200S, 07960 Morristown, New Jersey, United States
Research Article
Efficacy of UC-II ® Undenatured Type II Collagen on Knee Joint Function in Healthy Subjects: An Exploratory Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial
Author(s): Zainulabedin Saiyed, Shane Durkee, James Bowman and Vijaya Juturu*
UC-II® is a unique joint health ingredient derived from chicken sternum. In a previous study, UC-II® improved knee extension range of motion and extend exercise time before the onset of knee pain in healthy participants. The current exploratory post hoc analyses sought to assess items from the Knee Injury and Osteoarthritis Outcome Score (KOOS) in healthy participants aged ≥ 50 years who previously participated in a randomized controlled trial. All participants reported knee pain following a standardized stepmill test and were randomized to receive placebo or 40 mg UC-II® supplementation containing ≥ 3% (≥ 1.2 mg) undenatured type II collagen for 120 days. For the current post hoc analyses, 17 participants (UC-II® =9, placebo=8) met the acceptance criteria (age.. View More»