Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Department of Neurology, University of Mansoura, Mansoura, Egypt
Research Article
The Diagnostic Role of Brain MRI in Detection of Multiple Sclerosis Related Cognitive Impairment
Author(s): Wael M Gabr*, Mohamed Saad and Maha Bilal
Background: Cognitive Impairment (CI) is a common manifestation of Multiple Sclerosis (MS), which can severely
affect patients’ and their families’ life. Early suspicion and detection of CI can improve general medical management
of MS patients.
Objectives: To correlate MS related CI to cortical brain lesions using brain for Magnetic Resonance to Imaging (MRI).
Materials and methods: Cognitive of impairment was detected using to that Mini Mental State Examination (MMSE),
Neurological examination and brain MRI were performed for all patients. Correlation were calculated between
disease cortical burden detected by MRI and CI.
Results: Fifty-three patients with proven MS were scanned by brain MRI, 69.8% of them had cognitive impairment
diagnosed with mmSE. The presence.. View More»