ISSN: 2161-0487
+44 1478 350008
Department of Psychiatry, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Sydney, Australia
Mini Review
Treating Schizophrenia Thinking beyond the Choice of Antipsychotic
Author(s): William Lugg*
The treatment of schizophrenia has evolved over the past half century primarily in the context of antipsychotic drug
development. Although there has been significant progress resulting in the availability and use of numerous
medications, these reflect three basic classes of medications (conventional (typical), atypical and dopamine partial
agonist antipsychotics) all of which, despite working by varying mechanisms of actions, act principally on dopamine
systems. Many of the second-generation (atypical and dopamine partial agonist) antipsychotics are believed to offer
advantages over first-generation agents in the treatment for schizophrenia. However, the pharmacological properties
that confer the different therapeutic effects of the new generation of antipsychotic drugs have remained elusive, and
certain side effects can still impact patient health and quality of .. View More»
DOI:
10.35248/2161-0487.21.11.413