Cell & Developmental Biology

Cell & Developmental Biology
Open Access

ISSN: 2168-9296

+44 1478 350008

Xianhong Yu

Department of Medicine, Peking University, Peking-Tsinghua Center for Life Sciences, Beijing 100871, China

Publications
  • Research Article   
    The Comparison of Single-Cell RNA Sequencing Platforms Based Dropletsxianhong
    Author(s): Yulong Zhong, Linyan Wang and Xianhong Yu*

    Single-cell sequencing enables to reveal cellular heterogeneity and discover new cellular subpopulations. In terms of the strategy of single-cell sequencing, the main methods are based with combinatorial index, microwell and microfluidic. Due to the simplicity, methods based droplets are widely used for single-cell sequencing for multi-omics. Therefore, in order to facilitate researchers to choose a suitable platform to meet their application scenarios, we compared several commercial platforms: The Chromium X platform of 10x Genomics, the MobiNova-100 platform of MobiDrop, the SeekOne platform of SeekGene, and the C4 platform of BGI. Based the comprehensive assessment of the data analysis, the Chromium X platform shows an excellent performance, closely followed by MobiNova-100 platform... View More»

    Abstract PDF

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