Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, China
Dr. Xiaohui Wu is currently working as a Professor in Department of Neurosurgery in Zhongnan Hospital of Wuhan University. Xiaohui Wu area of research interests include Neurosurgery, Pediatric neurosurgery, Neuro-oncology.
Research Article
Elevated Serum Creatine Kinase as an Independent Prognostic Factor for
Mortality in Hospitalized Patients with COVID-19
Author(s): Xinghuan Wang*, Guang Zeng, Jinpeng Li, Xiaohui Wu*, Qian Wu, Yibin Yang, Wen Zeng, Sichao Chen, Yihui Huang, Danyang Chen, Liang Guo*, Qianqian Li and Zeming Liu
Objective: We aimed to investigate the effect of serum Creatine Kinase (CK) levels on disease progression and prognosis in coronavirus disease 2019 (COVID-19).
Methods: This was a retrospective study of 1751 COVID-19 patients at Leishenshan hospital in Wuhan, China. All patients were grouped to normal and elevated CK groups. Univariate and multivariate Cox regression analyses were performed to explore the relationship between mortality and CK levels. Univariate and multivariate logistic regression analyses were performed to explore the relationship between disease severity and CK levels. Survival curves were generated for normal and elevated CK groups. Fitting curves were performed to investigate the relationships between the number of days in hospital and Computed Tomography (CT) score.
Results: Elevated CK patien.. View More»
DOI:
10.35248/igoa.21.6.135