Journal of Cell Science & Therapy
Open Access

Department of Cardiology, Southwest Medical University, Luzhou, China

Publications

• Short Communication   
  Frontier Progress on the Role and Mechanism of Ion Channels on Vascular Wall Cells in Vascular Fibrosis Remodeling
  Author(s): Xin Liao, Xiaolin Zhang, Hai Tian and Jun Cheng*
  
  Fibrosis is often an end-stage manifestation of chronic inflammatory diseases, affecting any tissue or organ in the body due to uncontrolled deposition of extracellular matrix molecules. Vascular fibrosis, characterized by the accumulation of extracellular matrix components, leads to vessel stiffness and is associated with various cardiovascular diseases. Ion channels in the cardiovascular system are important for maintaining normal physiological functions and play significant roles in processes such as ion transport and cell differentiation. Ion channels on fibroblasts, smooth muscle cells, and endothelial cells may be involved in vascular fibrotic remodeling. Understanding the mechanisms of vascular fibrosis and reversing this pathology could enhance our knowledge and treatment of fibrosis. This letter discusses ion channels known to contribute to vascular fibrotic remodeling and po.. View More»
  DOI: 10.35248/2157-7013.25.16.492

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