Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China
Wang Xinghuan, male (1965-), doctor of medicine, chief physician, professor (second level), doctoral tutor, chief scientist of the national 13th five-year key special project, winner of the second prize of the National Technical Invention Award, national Young and middle-aged experts with outstanding contributions to health and family planning, Luojia outstanding scholars of the "351 Talent Program" of Wuhan University, the first and second leading medical talents in Hubei Province, and experts enjoying special allowances from the State Council. He is currently the dean of Zhongnan Hospital of Wuhan University, the leader of urology and evidence-based and translational medicine.
Research Article
Elevated Serum Creatine Kinase as an Independent Prognostic Factor for
Mortality in Hospitalized Patients with COVID-19
Author(s): Xinghuan Wang*, Guang Zeng, Jinpeng Li, Xiaohui Wu*, Qian Wu, Yibin Yang, Wen Zeng, Sichao Chen, Yihui Huang, Danyang Chen, Liang Guo*, Qianqian Li and Zeming Liu
Objective: We aimed to investigate the effect of serum Creatine Kinase (CK) levels on disease progression and prognosis in coronavirus disease 2019 (COVID-19).
Methods: This was a retrospective study of 1751 COVID-19 patients at Leishenshan hospital in Wuhan, China. All patients were grouped to normal and elevated CK groups. Univariate and multivariate Cox regression analyses were performed to explore the relationship between mortality and CK levels. Univariate and multivariate logistic regression analyses were performed to explore the relationship between disease severity and CK levels. Survival curves were generated for normal and elevated CK groups. Fitting curves were performed to investigate the relationships between the number of days in hospital and Computed Tomography (CT) score.
Results: Elevated CK patien.. View More»
DOI:
10.35248/igoa.21.6.135