ISSN: 2167-0870
Department of Pharmacy, Shandong University of Chinese Medicine, Jinan, 250355, China
Dr. Xiuli Zu is currently working in Department of Pharmacy, Shandong University of Chinese Medicine, Jinan, 250355, China. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended his valuable service towards the scientific community with his extensive research work.
Research Article
Therapeutic Targets and Mechanism of Banxia Xiexin Decoction on Precancerous Lesions of Gastric Cancer: Network Pharmacology
Author(s): Guoxiu Zu, Keyun Sun, Ling Li, Xiuli Zu, Tao Han and Hailiang Huang*
Background: Precancerous Lesions of Gastric Cancer (PLGC) is a common gastrointestinal tract and digestive system disease
that lacks effective therapeutic drugs with good curative effects and few adverse reactions. Traditional Chinese medicine
(TCM) has the advantages of multiple components, multiple channels, and fewer adverse reactions in the treatment of PLGC.
Although Banxia Xiexin Decoction (BXD) demonstrates a good therapeutic effect on PLGC, the pharmacological mechanism
underlying its anticancer effect is still unclear.
Methods: We used a network pharmacology strategy, including the construction and analysis of a complex drug-disease
network, to explore the complex mechanism of BXD treatment of PLGC. In addition, molecular docking technology was used
to preliminarily study the binding ability of the potential active c.. View More»
DOI:
10.35248/2167-0870.21.s12.003