Applied Microbiology: Open Access
Open Access

Department of Tropical Medicine and Gastroenterology, Minia University, Minia, Egypt

Publications

• Research Article   
  Vonoprazan-Based Versus Esomeprazole-Based Triple Therapy for Helicobacter pylori: A Randomized Trial
  Author(s): Yasser A. Abdelghani* and Mahmoud M. Moussa
  
  Background: Vonoprazan is indeed a potassium-competitive acid blocker that exhibits acid inhibiting effects that are more powerful and longer-lasting than those produced by Proton Pump Inhibitors (PPIs). Aim and objective: To compare between the effectiveness of two 14-day regimens; one based on vonoprazan and the other on esomeprazole, to eradicate H. pylori. Patients and methods: This randomized clinical trial was performed at minia university hospital. Participants who were determined to have active H. pylori infection and were either untreated or had previously received therapy were randomly assigned to either the VAL group (vonoprazan 20 mg bid, amoxicillin 1000 mg bid, plus levofloxacin 500 mg once day) or the EAL group (Esomeprazole 20 mg bid., amoxicillin 1000 mg bid., and levofloxacin 500 mg once daily). After 4-6 weeks following th.. View More»
  DOI: 10.35248/2471-9315.23.9.258

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