Journal of Clinical Trials
Open Access

Department of Research and Development, Shreepad Shree Vallabh SSV Phytopharmaceuticals, Mumbai, Maharashtra, India

Publications

• Research Article   
  Mechanistic Understanding of Novel Herbomineral Formulation Curvic^® in the Management of Viral Outbreaks
  Author(s): Yogesh Arun Dound*
  
  The ongoing SARS-CoV-2 pandemic has disrupted health systems worldwide. SARS-CoV-2 is constantly evolving and multiple newer Variants of Concern (VOC) such as Delta and Omicron have emerged. Therefore, there is a need for drugs which can be achieved by targeting the proteins that are conservative and less susceptible to mutations and can initialize T cells activation. The viral polymerases such as PLpro (nsp3), 3CLpro (nsp5), and RdRP (nsp12), proteins critical for viral replication, are highly conserved in RNA viruses. Targeting this unique subset of viral replication proteins may prove effective against a wide range of VOC. Notably, when T cells encounter an antigen that their receptors recognize, they undergo self-replication and produce more immune cells. Hence, the immune characterization and identification of the T-cell immune epitopes for key viral repli.. View More»
  DOI: 10.35248/2167-0870.22.S19.007

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