ISSN: 2167-0250
+44 1300 500008
Department of Horse, Companion and Wild Animal Science, Kyungpook National University, Sangju 37224, Korea
Mini Review
Can Oxytocin be used as a Treatment for Sub/Infertility of Males of Seasonal Breeders?
Author(s): Minjung Yoon* and Youngwook Jung
Oxytocin (OXT) is a critical endocrine, paracrine and autocrine factor in male reproductive system. In seasonal
breeders, the expression of OXT and its receptor (OXTR) were observed in germ cells, Sertoli cells, Leydig cells, and
the membrane of the seminiferous tubules, indicating that OXT plays roles in spermatogenesis and steroidogenesis.
OXT and OXTR were expressed in epithelial cells and smooth muscle cells in the epididymis as well as the epithelial
cells in ductus deferens, suggesting that OXT is involved in the sperm transportation. The intensity of OXT and
OXTR expression was significantly higher in the breeding season than in the non-breeding season. Several studies
demonstrated that the size of reproductive organs and the rate of sperm production vary depending on the season.
These results implied that OXT and OXTR systems appear to be important factors.. View More»
DOI:
10.35248/2167-0250.22.S1.004