Drug Designing: Open Access
Open Access

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia

Biography

Dr.Yury N. Vorobjev is currently working at Chemical Biology and Fundamental Medicine Department. Dr. is research interests includes Pharmacy in SARS-cov-2. Dr. serving as an editorial member and reviewer of several international reputed journals. Dr. has successfully completed his Administrative responsibilities. Dr. has authored of many research articles/books related to Medicine.

Publications

• Research Article   
  Design of Effective Molecular Blocker of E Protein Channel as Anti SARS-Cov-2 Virus Drug
  Author(s): Yury N. Vorobjev*
  
  Design of a drug compound that can effectively bind to the E channel and block the diffusion of hydrogen (H+) and K+ ions through channel and inhibit virus life cycle and replication is an important task. A new class of positively charged, +2 e.u., molecules is proposed here to block proton diffusion trough the E channel. Several drug candidates, derivatives of a lead compound (diazabicyclooctane), were proposed and investigated drug binding energy and positions. E protein has in-channe l and out of channelbinding sites of high affinity for suggested molecular blockers. The most promising structure of E channel blocker is suggested... View More»
  DOI: 10.35248/2169-0138.21.10.e186

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